Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 8/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455718 | 1.00 | FOLH1 (0.51) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL8509636 | 0.88 | FOLH1 (0.47) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL50111 | 0.87 | FOLH1 (0.57) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL43620 | 0.87 | FOLH1 (0.57) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL25396641 | 0.85 | FOLH1 (0.51) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| Water SCHEMBL380638 | 0.85 | FOLH1 (0.56) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL20528926 | 0.85 | FOLH1 (0.51) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL901403 | 0.85 | FOLH1 (0.56) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| SCHEMBL380767 | 0.85 | FOLH1 (0.56) | FOLH1GSRSLC6A5RNPEPCPB2 | |
| Water SCHEMBL28073715 | 0.85 | FOLH1 (0.56) | FOLH1GSRSLC6A5RNPEPCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287383-A1 | PYRROLYSYL-tRNA SYNTHETASE VARIANTS AND USES THEREOF | ENGENES BIOTECH GMBH (AT) | 2023-09-14 | — | — | US | claimed |
| WO-2018185222-A1 | AMINOACYL TRNA SYNTHETASES AND ORTHOGONAL TRNAS | ACIB GMBH - AUSTRIAN CENTRE OF INDUSTRIAL BIOTECHNOLOGY (AT) | 2018-10-11 | — | — | WO | claimed |
| US-20230287383-A1 | PYRROLYSYL-tRNA SYNTHETASE VARIANTS AND USES THEREOF | ENGENES BIOTECH GMBH (AT) | 2023-09-14 | — | — | US | disclosed |