Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ILK | Q13418 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13683169 | 0.78 | IKBKB (0.46) | ADORA2AADORA2BGAALMNAALOX15 | |
| SCHEMBL33899 | 0.77 | GAA (0.42) | ADORA2AADORA2BGAALMNAALOX15 | |
| SCHEMBL17740400 | 0.77 | ADORA2A (0.42) | ADORA2AADORA2BGAALMNAALOX15 | |
| SCHEMBL13741598 | 0.77 | ADORA2A (0.45) | ADORA2AADORA2BGAALMNAALOX15 | |
| Hydrochloric Acid SCHEMBL4669106 | 0.76 | GAA (0.41) | ADORA2AADORA2BGAALMNAALOX15 | |
| SCHEMBL14606458 | 0.76 | ADORA2A (0.41) | ADORA2AADORA2BGAALMNAALOX15 | |
| SCHEMBL23398958 | 0.74 | ADORA2A (0.39) | ADORA2AADORA2BGAALMNAALOX15 | |
| SCHEMBL20610900 | 0.74 | ADORA2A (0.39) | ADORA2AADORA2BGAALMNAMAPT | |
| SCHEMBL16200210 | 0.74 | ALDH1A1 (0.46) | ADORA2AADORA2BGAALMNAALOX15 | |
| SCHEMBL12806577 | 0.74 | ADORA2A (0.39) | ADORA2AADORA2BGAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018185236-A1 | PZRAYOLE DERIVATIVES USED AS INVERSE AGONISTS OF THE ROR GAMMA (T) RETINOID-RELATED ORPHAN GAMMA RECEPTOR | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2018-10-11 | — | — | WO | disclosed |