Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22076498 | 0.94 | MAPT (0.64) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL22076496 | 0.94 | MAPT (0.67) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL28736744 | 0.87 | PKM (0.68) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL10676155 | 0.86 | SMN1; SMN2 (0.68) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL392573 | 0.86 | SMN1; SMN2 (0.85) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL28863418 | 0.85 | SMN1; SMN2 (0.75) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| Methyl 3-(3-Indolylmethyl)Propanoate SCHEMBL290808 | 0.85 | MAPT (0.71) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL23970011 | 0.84 | MAPT (0.62) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL10031559 | 0.84 | MAPT (0.62) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL12966475 | 0.83 | SMN1; SMN2 (0.67) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3606325-A1 | RATIONAL DESIGN OF MICROBIAL-BASED BIOTHERAPEUTICS | Gusto Global, LLC (US) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018187272-A1 | RATIONAL DESIGN OF MICROBIAL-BASED BIOTHERAPEUTICS | GUSTO GLOBAL, LLC (US) | 2018-10-11 | — | — | WO | disclosed |