Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9860218 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL1398377 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL8334388 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL184066 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL9860216 | 1.00 | CES2 (0.55) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL5612656 | 0.97 | CES2 (0.50) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL9709409 | 0.97 | CES2 (0.50) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL5612649 | 0.97 | CES2 (0.50) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL304440 | 0.94 | CES2 (0.48) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL304438 | 0.94 | CES2 (0.48) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3387931-B1 | VULCANIZABLE COMPOSITION COMPRISING HXNBR LATEX AND POLYFUNCTIONAL EPOXIDE | ARLANXEO DEUTSCHLAND GMBH (DE) | 2020-07-15 | — | — | EP | disclosed |
| WO-2018188966-A1 | VULCANIZABLE COMPOSITION CONTAINING HXNBR LATEX AND POLYFUNCTIONAL EPOXIDE | ARLANXEO DEUTSCHLAND GMBH (DE) | 2018-10-18 | — | — | WO | disclosed |
| EP-3387931-A1 | VULCANIZABLE COMPOSITION COMPRISING HXNBR LATEX AND POLYFUNCTIONAL EPOXIDE | ARLANXEO Deutschland GmbH (DE) | 2018-10-17 | — | — | EP | disclosed |