Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 6/20 | 0.39 |
| ▸ | MET | P08581 | 12/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530371 | 0.89 | MET (0.43) | METSLC22A12 | |
| SCHEMBL20530349 | 0.88 | MET (0.48) | METCDKL5 | |
| SCHEMBL20530351 | 0.88 | GRIN2B (0.39) | GRIN2BMETKDM4EALDH1A1HPGD | |
| SCHEMBL20530342 | 0.87 | MET (0.41) | GRIN2BMETKDM4EALDH1A1HPGD | |
| SCHEMBL20530317 | 0.87 | MET (0.40) | METSLC22A12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20530315 | 0.87 | MET (0.40) | METCDKL5 | |
| SCHEMBL20530303 | 0.87 | MET (0.49) | METKDM4ECDKL5 | |
| SCHEMBL20530361 | 0.86 | MET (0.40) | METCDKL5 | |
| SCHEMBL1330396 | 0.86 | MET (0.52) | METCDKL5 | |
| SCHEMBL20530357 | 0.85 | MEN1 (0.42) | METCDKL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571878-B1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INCOZEN THERAPEUTICS PVT LTD (IN) | 2018-10-17 | — | — | EP | claimed |