Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530471 | 1.00 | CA1 (0.50) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL20530465 | 1.00 | CA1 (0.50) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL20530467 | 1.00 | CA1 (0.50) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL20530473 | 1.00 | CA1 (0.50) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL2532757 | 0.79 | MEN1 (0.46) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL4841239 | 0.79 | MEN1 (0.46) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL4833311 | 0.79 | MEN1 (0.46) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL6480813 | 0.79 | MEN1 (0.46) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL4833417 | 0.79 | MEN1 (0.46) | CA1CA2CA7CA9CYP3A4 | |
| SCHEMBL9025636 | 0.75 | PSEN1 (0.41) | CYP3A4TSHRMEN1KMT2ASLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165640-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | SUSTAINABLE MOMENTUM, S.L. (ES) | 2020-05-28 | — | — | US | disclosed |
| CN-110945122-A | Fructose-6-phosphate aldolase variants for aldol condensation carbon linking | 西班牙高等科研理事会 | 2020-03-31 | — | — | CN | disclosed |
| EP-3388518-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2018-10-17 | — | — | EP | disclosed |