Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052420 | 0.89 | CAPN1 (0.38) | CAPN1ALDH1A1 | |
| SCHEMBL1992956 | 0.84 | CAPN1 (0.50) | CAPN1 | |
| SCHEMBL2051517 | 0.82 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL2046422 | 0.80 | CAPN1 (0.55) | CAPN1 | |
| SCHEMBL2048051 | 0.80 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL2047939 | 0.78 | CAPN1 (0.47) | CAPN1 | |
| SCHEMBL1994167 | 0.74 | CAPN1 (0.53) | CAPN1 | |
| SCHEMBL1996199 | 0.74 | CAPN1 (0.48) | CAPN1 | |
| SCHEMBL1992804 | 0.74 | CAPN1 (0.55) | CAPN1 | |
| SCHEMBL1986120 | 0.73 | CAPN1 (0.53) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516393-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | Abbott GmbH & Co. KG (DE) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011076811-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO. KG (DE) | 2011-06-30 | — | — | WO | disclosed |