Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251765 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 | |
| SCHEMBL3240363 | 0.86 | HTR2C (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL29936364 | 0.86 | HTR2C (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL13507486 | 0.86 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ACYP2C19NPSR1 | |
| SCHEMBL29936064 | 0.86 | HTR2C (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL24179626 | 0.86 | HTR2C (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL384788 | 0.86 | HTR2C (0.53) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL3167480 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL5761224 | 0.85 | PREP (0.50) | SMN1; SMN2NPC1RAB9ACYP2C19PREP | |
| SCHEMBL1694385 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ACYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165640-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | SUSTAINABLE MOMENTUM, S.L. (ES) | 2020-05-28 | — | — | US | disclosed |
| CN-110945122-A | Fructose-6-phosphate aldolase variants for aldol condensation carbon linking | 西班牙高等科研理事会 | 2020-03-31 | — | — | CN | disclosed |
| EP-3388518-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2018-10-17 | — | — | EP | disclosed |