Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 7/20 | 0.58 |
| ▸ | MDM4 | O15151 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16463752 | 1.00 | MDM2 (0.58) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL4600023 | 0.96 | MDM2 (0.57) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL30278748 | 0.96 | MDM2 (0.57) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL30854537 | 0.96 | MDM2 (0.57) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL4600019 | 0.96 | MDM2 (0.57) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL25362302 | 0.96 | MDM2 (0.57) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL8892538 | 0.93 | MDM2 (0.60) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL8893047 | 0.93 | MDM2 (0.60) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL15681926 | 0.93 | MDM4 (0.59) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL389249 | 0.93 | MDM4 (0.59) | MDM2MDM4TP53TLR2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110366556-B | Antibacterial peptide macrocyclic compounds and uses thereof | 豪夫迈·罗氏有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-3388444-A1 | ANTI-BACTERIAL PEPTIDE MACROCYCLES AND USE THEREOF | F. Hoffmann-La Roche AG (CH) | 2018-10-17 | — | — | EP | disclosed |