Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.60 |
| ▸ | MDM4 | O15151 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TLR2 | O60603 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892538 | 1.00 | MDM2 (0.60) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL8426773 | 0.94 | MDM2 (0.58) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL16744149 | 0.94 | TLR2 (0.66) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL16744148 | 0.94 | TLR2 (0.66) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL18614182 | 0.94 | TLR2 (0.66) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL16744151 | 0.94 | TLR2 (0.66) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL8425079 | 0.94 | MDM2 (0.55) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL12466711 | 0.94 | KMT2A (0.66) | MDM2MDM4TP53TLR2KMT2A | |
| SCHEMBL20357051 | 0.94 | TLR2 (0.66) | MDM2MDM4TP53TLR2CASP3 | |
| SCHEMBL19299530 | 0.94 | TLR2 (0.60) | MDM2MDM4TP53TLR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610141-A | CELL DIVISION STIMULANT | NYCOMED IMAGING AS (NO) | 1997-03-11 | — | — | US | disclosed |
| EP-0673388-A1 | DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY | NYCOMED IMAGING AS (NO) | 1995-09-27 | — | — | EP | disclosed |
| WO-1993024523-A1 | DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY | HAFSLUND NYCOMED AS (NO) | 1993-12-09 | — | — | WO | disclosed |