Isopulegol

Isopulegol

SCHEMBL20530682

C=C(C)[C@@H]1CC[C@@H](C)C[C@H]1O.CCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Isopulegol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.41
TRPM8 Q7Z2W7 2/20 0.41
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopulegol SCHEMBL8814863 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8815381 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL20681722 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8815146 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL12044788 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8814281 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL20903638 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL20903648 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL12451192 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4
Isopulegol SCHEMBL8632368 0.94 TRPA1 (0.45) TRPA1TRPM8CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10745332-B2 Process for purifying a crude composition including a monoterpene compound, such as a monocyclic monoterpene alcohol, by layer melt crystallization SULZER MANAGEMENT AG (CH) 2020-08-18 US disclosed
US-20200071249-A1 PROCESS FOR PURIFYING A CRUDE COMPOSITION INCLUDING A MONOTERPENE COMPOUND, SUCH AS A MONOCYCLIC MONOTERPENE ALCOHOL, BY LAYER MELT CRYSTALLIZATION SULZER MANAGEMENT AG (CH) 2020-03-05 US disclosed
EP-3606896-A1 A PROCESS FOR PURIFYING A CRUDE COMPOSITION INCLUDING A MONOTERPENE COMPOUND, SUCH AS A MONOCYCLIC MONOTERPENE ALCOHOL, BY LAYER MELT CRYSTALLIZATION Sulzer Management AG (CH) 2020-02-12 EP disclosed
WO-2018189386-A1 A PROCESS FOR PURIFYING A CRUDE COMPOSITION INCLUDING A MONOTERPENE COMPOUND, SUCH AS A MONOCYCLIC MONOTERPENE ALCOHOL, BY LAYER MELT CRYSTALLIZATION SULZER CHEMTECH AG (CH) 2018-10-18 WO disclosed
EP-3388411-A1 A PROCESS FOR PURIFYING A CRUDE COMPOSITION INCLUDING A MONOTERPENE COMPOUND, SUCH AS A MONOCYCLIC MONOTERPENE ALCOHOL, BY LAYER MELT CRYSTALLIZATION Sulzer Chemtech AG (CH) 2018-10-17 EP disclosed