SCHEMBL2053141

SCHEMBL2053141

Cc1ccc(C(Cc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.59
SLC6A4 P31645 3/20 0.59
SLC6A3 Q01959 3/20 0.59
SMN1; SMN2 Q16637 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CNR1 P21554 3/20 0.46
CNR2 P34972 2/20 0.46
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
HTR1A P08908 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
DRD2 P14416 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
HTR2A P28223 1/20 0.46
MC4R P32245 1/20 0.46
ADRA1A P35348 1/20 0.46
HRH1 P35367 1/20 0.46
OPRM1 P35372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29938176 0.98 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3SMN1; SMN2NPSR1
SCHEMBL4973916 0.96 SLC6A2 (0.53) SLC6A2SLC6A4SLC6A3SMN1; SMN2NPSR1
SCHEMBL10489055 0.93 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3SMN1; SMN2NPSR1
SCHEMBL10633353 0.87 CYP2C19 (0.50) SLC6A2SLC6A4SLC6A3SMN1; SMN2NPSR1
SCHEMBL318537 0.86 SLC6A2 (0.74) SLC6A2SLC6A4SLC6A3CNR1ADRB2
SCHEMBL924819 0.86 SLC6A2 (0.74) SLC6A2SLC6A4SLC6A3CNR1ADRB2
SCHEMBL13308481 0.85 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3SMN1; SMN2NPSR1
SCHEMBL8591546 0.84 SLC6A2 (0.55) SLC6A2SLC6A4SLC6A3SMN1; SMN2TDP1
Ammonia Solution, Strong SCHEMBL29114405 0.84 SLC6A2 (0.71) SLC6A2SLC6A4SLC6A3CNR1ADRB2
SCHEMBL12346035 0.83 SLC6A2 (0.46) SLC6A2SLC6A4SLC6A3SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1203207-A None JP disclosed
US-7956011-B2 Materials and methods for the photodirected synthesis of oligonucleotide arrays THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2011-06-07 US disclosed
US-20090270279-A1 Materials and Methods for the Photodirected Synthesis of Oligonucleotide Arrays THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2009-10-29 US disclosed
WO-2006117556-A2 MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2006-11-09 WO disclosed
JP-H01203207-A PITCH-COATING MATERIAL AND ITS PRODUCTION NKK CORP 1989-08-16 JP disclosed