Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893286 | 1.00 | LTA4H (0.75) | LTA4H | |
| SCHEMBL1010362 | 0.91 | LTA4H (0.76) | LTA4H | |
| SCHEMBL2052615 | 0.91 | LTA4H (0.76) | LTA4H | |
| SCHEMBL1886734 | 0.91 | LTA4H (0.76) | LTA4H | |
| SCHEMBL29896963 | 0.89 | LTA4H (0.75) | LTA4H | |
| SCHEMBL4421786 | 0.89 | LTA4H (0.75) | LTA4H | |
| SCHEMBL1892625 | 0.89 | LTA4H (0.75) | LTA4H | |
| SCHEMBL1893094 | 0.87 | LTA4H (0.77) | LTA4H | |
| SCHEMBL2053066 | 0.86 | LTA4H (0.63) | LTA4H | |
| SCHEMBL1889547 | 0.86 | LTA4H (0.63) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336125-A1 | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | Janssen Pharmaceutica N.V. (BE) | 2011-06-22 | — | — | EP | disclosed |