Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.38 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21632313 | 0.82 | PTGFR (0.46) | PTGFRHIF1ACYP2C19TBXA2RLMNA | |
| SCHEMBL21631952 | 0.81 | PTGFR (0.39) | PTGFRHIF1ACYP2C19TBXA2RLMNA | |
| SCHEMBL365596 | 0.78 | SMN1; SMN2 (0.42) | PTGFRLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL20609516 | 0.78 | TDP1 (0.40) | LMNASMN1; SMN2KMT2ACASP3SENP8 | |
| SCHEMBL30686523 | 0.76 | DPP4 (0.40) | PTGFRLMNASMN1; SMN2KMT2A | |
| SCHEMBL21631978 | 0.75 | PTGFR (0.44) | PTGFRLMNASMN1; SMN2KMT2APTGDR2 | |
| SCHEMBL18994861 | 0.75 | KDM4E (0.33) | LMNAKMT2AALDH1A1TDP1 | |
| SCHEMBL3869346 | 0.73 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2KMT2AALDH1A1HTT | |
| SCHEMBL18668145 | 0.73 | HSD11B1 (0.39) | CYP2C19LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL179292 | 0.73 | TRPV1 (0.37) | LMNAKMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189011-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |