Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3446778 | 1.00 | TDP1 (0.75) | TDP1L3MBTL1TSHRSIGMAR1SPHK1 | |
| Phenol SCHEMBL28085364 | 0.93 | TDP1 (0.67) | TDP1L3MBTL1TSHRSPHK1HRH4 | |
| SCHEMBL4069939 | 0.91 | TDP1 (0.64) | TDP1L3MBTL1TSHRSIGMAR1IDO1 | |
| SCHEMBL9011734 | 0.91 | TSHR (0.67) | TDP1L3MBTL1TSHRIDO1HRH4 | |
| SCHEMBL9011646 | 0.91 | TSHR (0.67) | TDP1L3MBTL1TSHRIDO1HRH4 | |
| SCHEMBL9011624 | 0.91 | TSHR (0.67) | TDP1L3MBTL1TSHRIDO1HRH4 | |
| SCHEMBL9011715 | 0.91 | TSHR (0.67) | TDP1L3MBTL1TSHRIDO1HRH4 | |
| SCHEMBL1835993 | 0.91 | TDP1 (0.69) | TDP1L3MBTL1SPHK1 | |
| Phenol SCHEMBL28176899 | 0.90 | TDP1 (0.64) | TDP1L3MBTL1TSHRSPHK1IDO1 | |
| SCHEMBL7601255 | 0.89 | L3MBTL1 (0.68) | TDP1L3MBTL1TSHRSIGMAR1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609889-A1 | SMALL MOLECULES | University Of Dundee (GB) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189554-A1 | SMALL MOLECULES | UNIVERSITY OF DUNDEE (GB) | 2018-10-18 | — | — | WO | disclosed |