Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890177 | 0.85 | LTA4H (0.70) | LTA4HKCNH2 | |
| SCHEMBL1896304 | 0.84 | LTA4H (0.78) | LTA4HKCNH2 | |
| SCHEMBL1894183 | 0.84 | LTA4H (0.71) | LTA4HKCNH2 | |
| SCHEMBL1889643 | 0.78 | LTA4H (0.67) | LTA4HKCNH2 | |
| SCHEMBL1891356 | 0.76 | LTA4H (0.67) | LTA4HKCNH2 | |
| SCHEMBL1889489 | 0.76 | LTA4H (0.67) | LTA4HKCNH2 | |
| SCHEMBL3756787 | 0.76 | LTA4H (0.75) | LTA4H | |
| SCHEMBL2057465 | 0.75 | LTA4H (0.72) | LTA4HKCNH2 | |
| SCHEMBL1890064 | 0.75 | LTA4H (0.68) | LTA4HKCNH2 | |
| SCHEMBL1887431 | 0.74 | LTA4H (0.69) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336125-A1 | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | Janssen Pharmaceutica N.V. (BE) | 2011-06-22 | — | — | EP | disclosed |