Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826369 | 1.00 | ACP3 (0.45) | ACP3MEN1KMT2AADRA1DALDH1A1 | |
| SCHEMBL20526670 | 1.00 | ACP3 (0.45) | ACP3MEN1KMT2AADRA1DALDH1A1 | |
| SCHEMBL1614039 | 0.85 | MEN1 (0.53) | ACP3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8128064 | 0.85 | MEN1 (0.53) | ACP3MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9297066 | 0.83 | ACP3 (0.46) | ACP3MEN1KMT2AADRA1DALDH1A1 | |
| SCHEMBL9297070 | 0.83 | ACP3 (0.46) | ACP3MEN1KMT2AADRA1DALDH1A1 | |
| SCHEMBL30544183 | 0.83 | ACP3 (0.46) | ACP3MEN1KMT2AADRA1DALDH1A1 | |
| SCHEMBL7471497 | 0.81 | PARP1 (0.48) | ACP3MEN1KMT2AADRA1DPARP1 | |
| SCHEMBL22917154 | 0.81 | ACP3 (0.47) | ACP3MEN1KMT2AADRA1DALDH1A1 | |
| SCHEMBL661853 | 0.81 | KMT2A (0.48) | ACP3MEN1KMT2AHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609876-A1 | COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | The Regents of The University of Michigan (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018191199-A1 | COVALENT SMALL MOLECULE DCN1 INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-10-18 | — | — | WO | disclosed |