Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1216562 | 0.82 | NPSR1 (0.55) | LMNAKDM4EPTGS1PTGS2CYP1A2 | |
| SCHEMBL20534496 | 0.81 | GRIN1 (0.38) | LMNAKDM4ETSHRGRIN1GRIN2B | |
| SCHEMBL17324749 | 0.81 | ALDH1A1 (0.44) | LMNAKDM4EPTGS1PTGS2CYP1A2 | |
| SCHEMBL19675639 | 0.81 | ALDH1A1 (0.39) | LMNAKDM4EPTGS1PTGS2CYP1A2 | |
| SCHEMBL20534563 | 0.80 | PTGER4 (0.44) | LMNAKDM4EPTGS1PTGS2CYP1A2 | |
| SCHEMBL20250820 | 0.79 | ALDH1A1 (0.45) | LMNAKDM4EPTGS1PTGS2CYP1A2 | |
| SCHEMBL1215829 | 0.78 | ELANE (0.51) | LMNAKDM4EPTGS1PTGS2TSHR | |
| SCHEMBL17321439 | 0.78 | TSHR (0.46) | LMNAKDM4EPTGS1PTGS2CYP1A2 | |
| SCHEMBL15882054 | 0.76 | ELANE (0.57) | KDM4EALDH1A1 | |
| SCHEMBL20534551 | 0.76 | PTGER4 (0.41) | LMNAKDM4EPTGS1PTGS2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609883-A1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018188590-A1 | FLUORINE-SUBSTITUTED INDAZOLE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-10-18 | — | — | WO | disclosed |