Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 17/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20855727 | 0.84 | CTSA (0.49) | CTSA | |
| SCHEMBL1208785 | 0.83 | CTSA (0.50) | CTSA | |
| SCHEMBL22692590 | 0.83 | ADRA1A (0.54) | CTSAFFAR1 | |
| SCHEMBL2691040 | 0.82 | CTSA (0.48) | CTSA | |
| SCHEMBL1207026 | 0.82 | POLB (0.57) | CTSAFFAR1 | |
| SCHEMBL30040417 | 0.82 | POLB (0.57) | CTSAFFAR1 | |
| SCHEMBL17755382 | 0.82 | KDM4E (0.46) | — | |
| SCHEMBL16737884 | 0.81 | HTR2A (0.40) | CTSA | |
| SCHEMBL16737885 | 0.81 | HTR2A (0.40) | CTSA | |
| SCHEMBL21632110 | 0.80 | KMT2A (0.48) | CTSAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189011-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-10-18 | — | — | WO | disclosed |