Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9459401 | 0.79 | KDM4E (0.47) | CCR1CCR5CCR8CYP3A4MAPT | |
| SCHEMBL19443604 | 0.78 | SMN1; SMN2 (0.47) | CYP3A4MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL353204 | 0.76 | KDM4E (0.40) | CCR1CCR5CCR8MAPTKDM4E | |
| SCHEMBL30639525 | 0.75 | CA12 (0.46) | CYP3A4MAPTKDM4EKMT2APDE10A | |
| SCHEMBL5780556 | 0.75 | KDM4E (0.50) | CYP3A4MAPTKDM4EKMT2AASPH | |
| SCHEMBL31633613 | 0.75 | KDM4E (0.50) | CYP3A4MAPTKDM4EKMT2AASPH | |
| Hydrochloric Acid SCHEMBL4249059 | 0.75 | KDM4E (0.39) | CCR1CCR5CCR8KDM4EKMT2A | |
| SCHEMBL9504653 | 0.75 | KDM4E (0.39) | CCR1CCR5CCR8MAPTKDM4E | |
| SCHEMBL29956056 | 0.75 | CCR1 (0.45) | CCR1CCR5CCR8KDM4EKMT2A | |
| SCHEMBL3806777 | 0.75 | CCR1 (0.45) | CCR1CCR5CCR8KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12472271-B2 | HDAC6 inhibitors and imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2025-11-18 | — | — | US | disclosed |
| EP-4397656-A2 | HDAC6 INHIBITORS AND IMAGING AGENTS | The General Hospital Corporation (US) | 2024-07-10 | — | — | EP | disclosed |
| US-20240148915-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2024-05-09 | — | — | US | disclosed |
| EP-3609864-B1 | HDAC6 INHIBITORS AND IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11890356-B2 | HDAC6 inhibitors and imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2024-02-06 | — | — | US | disclosed |
| US-20220133916-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-05-05 | — | — | US | disclosed |
| US-11207431-B2 | HDAC6 inhibitors and imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2021-12-28 | — | — | US | disclosed |
| US-20200054773-A1 | HDAC6 Inhibitors and Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2020-02-20 | — | — | US | disclosed |
| EP-3609864-A1 | HDAC6 INHIBITORS AND IMAGING AGENTS | The General Hospital Corporation (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018191360-A1 | HDAC6 INHIBITORS AND IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054773-A1 | HDAC6 Inhibitors and Imaging Agents | HDAC1, HDAC6, HDAC11 | CCR1 2427/4885CCR5 3123/4885CCR8 2938/4885 |
| US-11207431-B2 | HDAC6 inhibitors and imaging agents | HDAC1, HDAC6, HDAC11 | CCR1 2427/4885CCR5 3123/4885CCR8 2938/4885 |
| US-20240148915-A1 | HDAC6 Inhibitors and Imaging Agents | HDAC1, HDAC6, HDAC11 | CCR1 2427/4885CCR5 3123/4885CCR8 2938/4885 |
| US-12472271-B2 | HDAC6 inhibitors and imaging agents | HDAC1, HDAC6, HDAC11 | CCR1 2427/4885CCR5 3123/4885CCR8 2938/4885 |
| US-11890356-B2 | HDAC6 inhibitors and imaging agents | HDAC1, HDAC6, HDAC11 | CCR1 2427/4885CCR5 3123/4885CCR8 2938/4885 |
| US-20220133916-A1 | HDAC6 Inhibitors and Imaging Agents | HDAC1, HDAC6, HDAC11 | CCR1 2427/4885CCR5 3123/4885CCR8 2938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.