Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 9/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.40 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806777 | 1.00 | CCR1 (0.45) | CCR1CCR5CCR8ALDH1A1KDM4E | |
| SCHEMBL4796219 | 0.78 | CCR1 (0.54) | CCR1CCR5CCR8ALDH1A1KDM4E | |
| SCHEMBL7675195 | 0.78 | CCR1 (0.48) | CCR1CCR5CCR8KDM4EMEN1 | |
| SCHEMBL28943229 | 0.77 | CCR1 (0.47) | CCR1CCR5CCR8KDM4EMEN1 | |
| SCHEMBL18052210 | 0.77 | ERN1 (0.48) | CCR1CCR5CCR8KDM4EMEN1 | |
| SCHEMBL29956628 | 0.75 | CCR1 (0.45) | CCR1CCR5CCR8ALDH1A1KDM4E | |
| SCHEMBL29954640 | 0.75 | CCR1 (0.45) | CCR1CCR5CCR8ALDH1A1KDM4E | |
| SCHEMBL17984975 | 0.75 | CCR1 (0.45) | CCR1CCR5CCR8ALDH1A1KDM4E | |
| SCHEMBL16237972 | 0.75 | CCR1 (0.45) | CCR1CCR5CCR8KDM4EMEN1 | |
| SCHEMBL29956546 | 0.75 | CCR1 (0.45) | CCR1CCR5CCR8ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |