SCHEMBL20535362

SCHEMBL20535362

O=C(NSc1ccccc1)Nc1cc[c]cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.47
TP53 P04637 2/20 0.47
EPHX1 P07099 1/20 0.47
TSHR P16473 1/20 0.47
EPHX2 P34913 1/20 0.47
CDK9 P50750 1/20 0.47
CLK4 Q9HAZ1 1/20 0.47
KMT2A Q03164 5/20 0.44
MEN1 O00255 4/20 0.44
MAPT P10636 4/20 0.44
POLB P06746 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CASP3 P42574 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
RAB9A P51151 5/20 0.40
NPC1 O15118 4/20 0.40
TAAR1 Q96RJ0 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751586 0.80 SMN1; SMN2 (0.74) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL132621 0.78 SMN1; SMN2 (0.46) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL23447277 0.77 NPC1 (0.54) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL10998968 0.75 SMN1; SMN2 (0.42) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL9721632 0.72 CYP1A2 (0.47) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL11685282 0.72 MAOA (0.41) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL1276401 0.71 SMN1; SMN2 (0.47) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL6793722 0.70 SMN1; SMN2 (0.63) SMN1; SMN2TP53EPHX1TSHREPHX2
SCHEMBL4797277 0.70 NPC1 (0.62) SMN1; SMN2TP53KMT2AMEN1MAPT
SCHEMBL23447724 0.70 MAPT (0.71) SMN1; SMN2TP53EPHX2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11697707-B2 Chemical sensors based on carbon nanotubes functionalised by conjugated polymers for analysis in aqueous medium ECOLE POLYTECHNIQUE (FR) 2023-07-11 US disclosed
US-20210130540-A1 CHEMICAL SENSORS BASED ON CARBON NANOTUBES FUNCTIONALISED BY CONJUGATED POLYMERS FOR ANALYSIS IN AQUEOUS MEDIUM CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-05-06 US disclosed
EP-3609881-A1 CHEMICAL SENSORS BASED ON CARBON NANOTUBES FUNCTIONALISED BY CONJUGATED POLYMERS FOR ANALYSIS IN AQUEOUS MEDIUM Ecole Polytechnique (FR) 2020-02-19 EP disclosed
CN-110691780-A Chemical sensor based on carbon nanotubes functionalized by conjugated polymers for analysis in aqueous media 巴黎综合理工大学 2020-01-14 CN disclosed
WO-2018189479-A1 CHEMICAL SENSORS BASED ON CARBON NANOTUBES FUNCTIONALISED BY CONJUGATED POLYMERS FOR ANALYSIS IN AQUEOUS MEDIUM ECOLE POLYTECHNIQUE (FR) 2018-10-18 WO disclosed