Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 0.54 |
| ▸ | FNTB | P49356 | 13/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20657039 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL28193348 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL1529433 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL4025174 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL359894 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL28784346 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL1820771 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL359893 | 1.00 | FNTA (0.54) | FNTAFNTBALDH1A1MAPTPGGT1B | |
| SCHEMBL11856516 | 0.98 | FNTA (0.51) | FNTAFNTBALDH1A1MAPT | |
| SCHEMBL3860439 | 0.98 | FNTA (0.51) | FNTAFNTBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3661413-A1 | BIOMARKERS ASSOCIATED WITH PARKINSON'S DISEASE | Cove Bio LLC (US) | 2020-06-10 | — | — | EP | claimed |
| WO-2019028106-A1 | BIOMARKERS ASSOCIATED WITH PARKINSON'S DISEASE | COVE BIO LLC (US) | 2019-02-07 | — | — | WO | claimed |
| EP-3610029-A1 | ASSAYS FOR SCREENING ACTIVITY OF MODULATORS OF MEMBERS OF THE HYDROXYSTEROID (17-BETA) DEHYDROGENASE (HSD17B) FAMILY | Regeneron Pharmaceuticals, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018190970-A1 | ASSAYS FOR SCREENING ACTIVITY OF MODULATORS OF MEMBERS OF THE HYDROXYSTEROID (17-BETA) DEHYDROGENASE (HSD17B) FAMILY | REGENERON PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | disclosed |