SCHEMBL4025174

SCHEMBL4025174

CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CN[C@H](CS)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FNTA P49354 14/20 0.54
FNTB P49356 13/20 0.54
ALDH1A1 P00352 1/20 0.51
MAPT P10636 1/20 0.51
PGGT1B P53609 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20657039 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL28193348 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL1529433 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL359894 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL28784346 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL1820771 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL359893 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL20535484 1.00 FNTA (0.54) FNTAFNTBALDH1A1MAPTPGGT1B
SCHEMBL11856516 0.98 FNTA (0.51) FNTAFNTBALDH1A1MAPT
SCHEMBL3860439 0.98 FNTA (0.51) FNTAFNTBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009108713-A2 TOPICAL COMPOSITIONS AND METHODS UTILIZING PEPTIDES CONTAINING LIPID-MODIFIED CYSTEINE-CONTAINING PEPTIDES SIGNUM BIOSCIENCES, INC. (US) 2009-09-03 WO disclosed
US-20090155186-A1 Compositions and methods for treating inflammatory conditions SIGNUM BIOSCENCES, INC. (NJ) 2009-06-18 US disclosed
EP-1899480-A4 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS SIGNUM BIOSCIENCES INC (US) 2009-04-22 EP disclosed
EP-1899480-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS SIGNUM BIOSCIENCES, INC. (US) 2008-03-19 EP disclosed
WO-2006135894-A1 COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS SIGNUM BIOSCIENCES, INC. (US) 2006-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155186-A1 Compositions and methods for treating inflammatory conditions TNF, TRAF6, RELA FNTA 1480/4885FNTB 2976/4885ALDH1A1 2832/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.