⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20537191 | 0.95 | — | — | |
| SCHEMBL20536699 | 0.91 | — | — | |
| SCHEMBL20536947 | 0.87 | — | — | |
| SCHEMBL20537051 | 0.85 | — | — | |
| SCHEMBL3779056 | 0.83 | — | — | |
| SCHEMBL20537088 | 0.83 | — | — | |
| SCHEMBL20537210 | 0.82 | — | — | |
| SCHEMBL20536744 | 0.81 | TSHR (0.30) | — | |
| SCHEMBL20536275 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL20536970 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3392255-B1 | UNSATURATED BOND-CONTAINING BISSILYL COMPOUND AND MAKING METHOD | SHINETSU CHEMICAL CO (JP) | 2020-06-03 | — | — | EP | disclosed |
| CN-108727423-A | Bis-silyl compound containing unsaturated bond and preparation method | 信越化学工业株式会社 | 2018-11-02 | — | — | CN | disclosed |
| EP-3392255-A1 | UNSATURATED BOND-CONTAINING BISSILYL COMPOUND AND MAKING METHOD | Shin-Etsu Chemical Co., Ltd. (JP) | 2018-10-24 | — | — | EP | disclosed |