Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.70 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | FGF1 | P05230 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653646 | 1.00 | TDP1 (0.70) | TDP1FOLH1MEN1ABL1LMNA | |
| SCHEMBL25305424 | 1.00 | TDP1 (0.70) | TDP1FOLH1MEN1ABL1LMNA | |
| SCHEMBL7906513 | 0.99 | TDP1 (0.72) | TDP1FOLH1MEN1ABL1LMNA | |
| Biotin SCHEMBL15104961 | 0.96 | TDP1 (0.68) | TDP1FOLH1MEN1ABL1LMNA | |
| SCHEMBL29531469 | 0.93 | TDP1 (0.61) | TDP1FOLH1MEN1ABL1LMNA | |
| SCHEMBL4077964 | 0.89 | TDP1 (0.68) | TDP1FOLH1MEN1ABL1LMNA | |
| Biotin SCHEMBL29531755 | 0.87 | TDP1 (0.69) | TDP1FOLH1MEN1ABL1LMNA | |
| SCHEMBL23124403 | 0.86 | TDP1 (0.57) | TDP1FOLH1MEN1ABL1LMNA | |
| SCHEMBL625200 | 0.86 | TDP1 (0.57) | TDP1FOLH1MEN1ABL1LMNA | |
| SCHEMBL12098624 | 0.85 | TDP1 (0.83) | TDP1FOLH1MEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3391876-A1 | LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL | SDG, Inc. (US) | 2018-10-24 | — | — | EP | disclosed |