Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HLCS | P50747 | 6/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625200 | 1.00 | TDP1 (0.57) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL29531755 | 0.94 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3648687 | 0.90 | TDP1 (0.53) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8597261 | 0.88 | TDP1 (0.51) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2232070 | 0.87 | TDP1 (0.56) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL7906513 | 0.87 | TDP1 (0.72) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL20537346 | 0.86 | TDP1 (0.70) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28653646 | 0.86 | TDP1 (0.70) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL25305424 | 0.86 | TDP1 (0.70) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL15104961 | 0.85 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4031550-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | The University of Chicago (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-114728970-A | Optical proximity analysis of protein-protein interactions in cells | 芝加哥大学 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021055960-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO (US) | 2021-03-25 | — | — | WO | disclosed |