SCHEMBL20537392

SCHEMBL20537392

CNS(=O)(=O)OC1OC(C)(C)OC1c1ccsc1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.33
HSD17B10 Q99714 2/20 0.31
TSHR P16473 1/20 0.31
CPB1 P15086 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
HPGD P15428 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20537510 0.76
SCHEMBL20537561 0.74
SCHEMBL28368908 0.74 HSD17B10 (0.33) PKMHSD17B10TSHRCPB1KDM4E
SCHEMBL28368949 0.74 HSD17B10 (0.33) PKMHSD17B10TSHRCPB1KDM4E
SCHEMBL20537389 0.73
SCHEMBL18783366 0.73 HTR6 (0.31)
SCHEMBL28364844 0.73
SCHEMBL28369051 0.73
SCHEMBL28369148 0.73
SCHEMBL20537560 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3079686-B1 SULFAMATE DERIVATIVE COMPOUND FOR USE IN PREVENTING OR TREATING EPILEPSY BIO PHARM SOLUTIONS CO LTD (KR) 2018-10-24 EP claimed