Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15551653 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL28364920 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL29015087 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL17093339 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL15550283 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL17093301 | 0.84 | BACE1 (0.41) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL17093421 | 0.84 | BACE1 (0.41) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL16795859 | 0.84 | BACE1 (0.41) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL27085626 | 0.84 | BACE1 (0.41) | ALDH1A1MAPTITGA4BACE1CYP3A4 | |
| SCHEMBL27135633 | 0.84 | BACE1 (0.41) | ALDH1A1MAPTITGA4BACE1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106507667-B | Sulfamate derivatives for the prevention or treatment of epilepsy | 比皮艾思药物研发有限公司 | 2020-01-24 | — | — | CN | disclosed |
| EP-3079686-B1 | SULFAMATE DERIVATIVE COMPOUND FOR USE IN PREVENTING OR TREATING EPILEPSY | BIO PHARM SOLUTIONS CO LTD (KR) | 2018-10-24 | — | — | EP | disclosed |