SCHEMBL2053746

SCHEMBL2053746

C1=Cc2ccccc2OC1.[Fe].[Si]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 3/20 0.41
STS P08842 1/20 0.40
ABCG2 Q9UNQ0 1/20 0.37
ITGB2 P05107 1/20 0.37
ICAM1 P05362 1/20 0.37
ITGAL P20701 1/20 0.37
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
LMNA P02545 2/20 0.33
CRHBP P24387 2/20 0.33
CRHR2 Q13324 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HTT P42858 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2053744 1.00 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL299531 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL299533 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL323466 0.98 CYP2B6 (0.42) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL9640291 0.96 CYP2B6 (0.39) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL322036 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL322176 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL11367023 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
Methane SCHEMBL21110857 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL7917399 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175654-B2 Integrated fuel injector igniters suitable for large engine applications and associated methods of use and manufacture MCALISTER TECHNOLOGIES, LLC (US) 2015-11-03 US disclosed
US-20140224210-A1 INTEGRATED FUEL INJECTOR IGNITERS SUITABLE FOR LARGE ENGINE APPLICATIONS AND ASSOCIATED METHODS OF USE AND MANUFACTURE MCALISTER TECHNOLOGIES, LLC (US) 2014-08-14 US disclosed
US-8528519-B2 Integrated fuel injector igniters suitable for large engine applications and associated methods of use and manufacture MCALISTER TECHNOLOGIES, LLC (US) 2013-09-10 US disclosed
US-20130047954-A1 INTEGRATED FUEL INJECTOR IGNITERS SUITABLE FOR LARGE ENGINE APPLICATIONS AND ASSOCIATED METHODS OF USE AND MANUFACTURE MCALISTER TECHNOLOGIES, LLC (US) 2013-02-28 US disclosed
EP-2510218-A2 INTEGRATED FUEL INJECTOR IGNITERS SUITABLE FOR LARGE ENGINE APPLICATIONS AND ASSOCIATED METHODS OF USE AND MANUFACTURE McAlister Technologies, LLC (US) 2012-10-17 EP disclosed
US-8225768-B2 Integrated fuel injector igniters suitable for large engine applications and associated methods of use and manufacture MCALISTER TECHNOLOGIES, LLC (US) 2012-07-24 US disclosed
US-20110233308-A1 INTEGRATED FUEL INJECTOR IGNITERS SUITABLE FOR LARGE ENGINE APPLICATIONS AND ASSOCIATED METHODS OF USE AND MANUFACTURE MCALISTER TECHNOLOGIES, LLC (US) 2011-09-29 US disclosed
WO-2011071607-A2 INTEGRATED FUEL INJECTOR IGNITERS SUITABLE FOR LARGE ENGINE APPLICATIONS AND ASSOCIATED METHODS OF USE AND MANUFACTURE MCALISTER ROY E (US) 2011-06-16 WO disclosed
US-7786835-B2 Magnetic element and method of manufacturing magnetic element Simida Corp. (JP) 2010-08-31 US disclosed
US-7523542-B2 Method of manufacturing a magnetic element SUMIDA CORPORATION (JP) 2009-04-28 US disclosed
US-7449984-B2 Magnetic element and method of manufacturing magnetic element SUMIDA CORPORATION (JP) 2008-11-11 US disclosed
US-20060186978-A1 MAGNETIC ELEMENT AND METHOD OF MANUFACTURING MAGNETIC ELEMENT SUMIDA CORPORATION (JP) 2006-08-24 US disclosed
US-20060186979-A1 MAGNETIC ELEMENT AND METHOD OF MANUFACTURING MAGNETIC ELEMENT SUMIDA CORPORATION (JP) 2006-08-24 US disclosed
US-20060119461-A1 Magnetic element and method of manufacturing magnetic element SUMIDA CORPORATION (JP) 2006-06-08 US disclosed