SCHEMBL9640291

SCHEMBL9640291

C1=Cc2ccccc2OC1.[Co].[Fe].[Ni].[Si]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 3/20 0.39
STS P08842 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.34
ITGB2 P05107 1/20 0.34
ICAM1 P05362 1/20 0.34
ITGAL P20701 1/20 0.34
CA1 P00915 1/20 0.32
CA9 Q16790 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A1 P04798 4/20 0.31
CYP1A2 P05177 4/20 0.31
LMNA P02545 2/20 0.31
CRHBP P24387 2/20 0.31
CRHR2 Q13324 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8509034 0.98 CYP2B6 (0.40) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL3434973 0.98 CYP2B6 (0.40) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL28641591 0.96 CYP2B6 (0.39) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL29012356 0.96 CYP2B6 (0.39) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL27950725 0.96 CYP2B6 (0.39) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL11367023 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL11367029 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL130348 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL322176 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1
SCHEMBL2053746 0.96 CYP2B6 (0.41) CYP2B6STSABCG2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5120496-A STAINLESS WROUGHT AND CAST MATERIALS AND WELDING ADDITIVES FOR STRUCTURAL UNITS EXPOSED TO HOT, CONCENTRATED SULFURIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1992-06-09 US disclosed
US-5051233-A Acid resistance in iron, chrome, nickel and silicon alloy BAYER AKTIENGESELLSCHAFT (DE) 1991-09-24 US disclosed