Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.66 |
| ▸ | TUBB | P07437 | 1/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20538164 | 1.00 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538199 | 0.96 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538193 | 0.96 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538196 | 0.96 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538496 | 0.94 | HDAC3 (0.69) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL19800985 | 0.94 | HDAC3 (0.69) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538284 | 0.94 | HDAC3 (0.69) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538288 | 0.94 | HDAC3 (0.69) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538113 | 0.93 | HDAC1 (0.68) | ALDH1A1KDM4EHPGDNPSR1LMNA | |
| SCHEMBL20538109 | 0.93 | HDAC1 (0.68) | ALDH1A1KDM4EHPGDNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183230-B1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |