Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16796654 | 1.00 | TLR9 (0.42) | TLR9CYP3A4MAPK1ALDH1A1MEN1 | |
| SCHEMBL20537586 | 1.00 | TLR9 (0.42) | TLR9CYP3A4MAPK1ALDH1A1MEN1 | |
| SCHEMBL16973331 | 0.82 | TLR9 (0.46) | TLR9CYP3A4MAPK1ALDH1A1MEN1 | |
| SCHEMBL16796656 | 0.80 | TLR9 (0.44) | TLR9CYP3A4MAPK1ALDH1A1KDM4E | |
| SCHEMBL20538367 | 0.79 | TLR9 (0.41) | TLR9CYP3A4MAPK1ALDH1A1MEN1 | |
| SCHEMBL20537498 | 0.79 | TLR9 (0.41) | TLR9CYP3A4MAPK1ALDH1A1MEN1 | |
| SCHEMBL16795911 | 0.79 | TLR9 (0.41) | TLR9CYP3A4MAPK1ALDH1A1MEN1 | |
| SCHEMBL17093413 | 0.79 | TLR9 (0.46) | TLR9CYP3A4MAPK1ALDH1A1TSHR | |
| SCHEMBL16808529 | 0.79 | TLR9 (0.46) | TLR9CYP3A4MAPK1ALDH1A1TSHR | |
| SCHEMBL20537523 | 0.78 | HTR1A (0.40) | TLR9MAPK1TSHRTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3079685-B1 | SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN | BIO PHARM SOLUTIONS CO LTD (KR) | 2018-11-28 | — | — | EP | claimed |
| EP-3079686-B1 | SULFAMATE DERIVATIVE COMPOUND FOR USE IN PREVENTING OR TREATING EPILEPSY | BIO PHARM SOLUTIONS CO LTD (KR) | 2018-10-24 | — | — | EP | claimed |