Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20538635 | 1.00 | ALDH1A1 (0.61) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20538292 | 0.93 | KDM1A (0.66) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20537609 | 0.93 | BACE1 (0.65) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20538119 | 0.93 | HDAC1 (0.56) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20538289 | 0.93 | KDM1A (0.66) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20537923 | 0.93 | BCHE (0.66) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20537607 | 0.93 | BACE1 (0.65) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20538461 | 0.93 | KDM4E (0.64) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL20538593 | 0.93 | BCHE (0.73) | ALDH1A1KDM4EHPGDGAALMNA | |
| SCHEMBL19801021 | 0.93 | BCHE (0.66) | ALDH1A1KDM4EHPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183230-B1 | N-((3,4,5-TRIMETHOXYSTYRYL)ARYL)CINNAMAMIDE COMPOUNDS AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2018-10-24 | — | — | EP | claimed |