Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.80 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491011 | 0.89 | ALDH1A1 (0.80) | ALDH1A1HTTTSHRMAPK1SMN1; SMN2 | |
| Water SCHEMBL9478437 | 0.88 | ALDH1A1 (0.78) | ALDH1A1HTTTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL12641999 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNAGLAKDM4E | |
| SCHEMBL874264 | 0.83 | ALDH1A1 (0.55) | ALDH1A1CD274TSHRLMNAKDM4E | |
| SCHEMBL12459935 | 0.81 | CD274 (0.79) | ALDH1A1CD274HTTTSHRMAPK1 | |
| SCHEMBL5452564 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HTTTSHRMAPK1SMN1; SMN2 | |
| SCHEMBL12460078 | 0.79 | POLB (0.65) | ALDH1A1CD274TSHRMAPK1LMNA | |
| SCHEMBL15109544 | 0.77 | GAA (0.60) | ALDH1A1CD274TSHRMAPK1LMNA | |
| SCHEMBL2028821 | 0.75 | KDM4E (0.47) | ALDH1A1HTTTSHRMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9478599 | 0.75 | ALDH1A1 (0.71) | ALDH1A1HTTTSHRMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160192-A1 | BIARYL AMINO ACIDS AND THEIR USE IN DNA BINDING OLIGOMERS | SPIROGEN LIMITED (GB) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160192-A1 | BIARYL AMINO ACIDS AND THEIR USE IN DNA BINDING OLIGOMERS | PCNA, POLL, XPA | ALDH1A1 2642/4885CD274 3772/4885HTT 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.