SCHEMBL2053946

SCHEMBL2053946

CCCCC(C=O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.50
MAPK1 P28482 1/20 0.50
TSHR P16473 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GPR84 Q9NQS5 3/20 0.43
FFAR1 O14842 1/20 0.43
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
MAPT P10636 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
CHRM1 P11229 1/20 0.41
AKR1A1 P14550 1/20 0.41
CHRM3 P20309 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
ADRA1A P35348 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15622058 0.93 GPR84 (0.52) CA2MAPK1GPR84FFAR1SLC1A2
SCHEMBL15621929 0.93 GPR84 (0.52) CA2MAPK1GPR84FFAR1SLC1A2
SCHEMBL284704 0.93 GPR84 (0.52) CA2MAPK1GPR84FFAR1SLC1A2
SCHEMBL3684391 0.91 GPR84 (0.55) CA2GPR84FFAR1SLC1A2SLC1A1
SCHEMBL527477 0.91 GPR84 (0.55) CA2GPR84FFAR1SLC1A2SLC1A1
SCHEMBL4565528 0.91 GPR84 (0.55) CA2GPR84FFAR1SLC1A2SLC1A1
SCHEMBL17065011 0.91 GPR84 (0.55) CA2GPR84FFAR1SLC1A2SLC1A1
SCHEMBL10593068 0.91 GPR84 (0.55) CA2GPR84FFAR1SLC1A2SLC1A1
SCHEMBL30402557 0.91 GPR84 (0.55) CA2GPR84FFAR1SLC1A2SLC1A1
SCHEMBL28072170 0.91 GPR84 (0.55) CA2GPR84FFAR1SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108627647-A A kind of detection of posttranslational modification proteomics and quantitative approach 四川大学 2018-10-09 CN claimed
CN-103635577-B Microbial synthesis of aldehydes and corresponding alcohols 伊塞尔生物技术有限责任公司 2017-04-12 CN claimed
CN-104520426-A Biosynthetic pathways, recombinant cells, and methods UNIV MINNESOTA 2015-04-15 CN claimed
CN-103635577-A Microbial synthesis of aldehydes and corresponding alcohols EASEL BIOTECHNOLOGIES LLC 2014-03-12 CN claimed
EP-2336315-A2 Enzymatic encoding methods for efficient synthesis of large libraries Nuevolution A/S (DK) 2011-06-22 EP claimed
EP-1383718-B1 CONTINUOUS HYDROFORMYLATION PROCESS DSM IP ASSETS BV (NL) 2006-06-28 EP claimed
CN-1226619-C Method for detecting organic acid/amino acid metabolite in urine by gas chromatography-mass spectrometry of filter paper sheet AFFILIATED TONGJI HOSPITAL OF (CN) 2005-11-09 CN claimed
CN-1532544-A Method for detecting organic acid/amino acid metabolite in urine by gas chromatography-mass spectrometry of filter paper sheet 华中科技大学同济医学院附属同济医院 2004-09-29 CN claimed
US-20040138508-A1 Rapid, low temperature vacuum evaporator recovery of rhodium bisphosphite catalyst from high boiling point aldehydes without degradation DSM I.P. ASSETS B.V. (NL) 2004-07-15 US claimed
EP-1383718-A1 CONTINUOUS HYDROFORMYLATION PROCESS DSM IP Assets B.V. (NL) 2004-01-28 EP claimed
WO-2002083605-A1 CONTINUOUS HYDROFORMYLATION PROCESS DSM IP ASSETS B.V. (NL) 2002-10-24 WO claimed
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
CN-115607677-A Compound for preventing, preventing or treating microbial infection and preparation and application thereof 太阳雨林(北京)生物医药有限公司 2023-01-17 CN disclosed
CN-114569726-B Compound for preventing, preventing or treating microbial infection and preparation method and application thereof 太阳雨林(北京)生物医药有限公司 2022-10-28 CN disclosed
CN-114788872-A Compound for preventing, preventing or treating microbial infection and preparation and application thereof 太阳雨林(北京)生物医药有限公司 2022-07-26 CN disclosed
WO-1998019984-A1 PROCESS FOR THE PREPARATION OF AN ALDEHYDE DSM N.V. (NL) 1998-05-14 WO disclosed
EP-0839787-A1 Process for the preparation of an aldehyde DSM N.V. (NL) 1998-05-06 EP disclosed
WO-1997033854-A1 PROCESS TO PREPARE A TERMINAL ALDEHYDE DSM N.V. (NL) 1997-09-18 WO disclosed
CN-1144475-A Polyamino salts of alpha-hydroxyacids, alpha-ketoacids and related compounds UNILEVER PLC (NL) 1997-03-05 CN disclosed
US-4147830-A Recording sheet FUJI PHOTO FILM CO., LTD. (JP) 1979-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040138508-A1 Rapid, low temperature vacuum evaporator recovery of rhodium bisphosphite catalyst from high boiling point aldehydes without degradation VAPB, VAPA, MVD CA2 187/4885MAPK1 3388/4885TSHR 3352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.