Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.53 |
| ▸ | ACE | P12821 | 6/20 | 0.53 |
| ▸ | CPA1 | P15085 | 6/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22503806 | 1.00 | MME (0.53) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL20540700 | 1.00 | MME (0.53) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL22503668 | 0.93 | MME (0.52) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL22503746 | 0.89 | MME (0.48) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL22503807 | 0.89 | MME (0.44) | MMEACECPA1ACE2ERAP2 | |
| SCHEMBL22503684 | 0.87 | MME (0.57) | MMEACECPA1ACE2ERAP2 | |
| SCHEMBL20540709 | 0.85 | FNTA (0.48) | MMEACECPA1ACE2 | |
| SCHEMBL13925358 | 0.85 | KDM4E (0.53) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL22503741 | 0.85 | MME (0.46) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL22503689 | 0.84 | MME (0.49) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453699-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2022-09-27 | — | — | US | disclosed |
| US-20210054025-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | UNIV INDIANA RES & TECH CORP (US) | 2021-02-25 | — | — | US | disclosed |
| US-10793594-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2020-10-06 | — | — | US | disclosed |
| US-20180305402-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION | 2018-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793594-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | CD47, CGAS, FPR1 | MME 150/4885ACE 692/4885CPA1 934/4885 |
| US-20180305402-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | CD47, CGAS, FPR1 | MME 150/4885ACE 692/4885CPA1 934/4885 |
| US-11453699-B2 | Antimicrobial compounds and/or modulators of microbial infections and methods of using the same | CD47, CGAS, FPR1 | MME 150/4885ACE 692/4885CPA1 934/4885 |
| US-20210054025-A1 | ANTIMICROBIAL COMPOUNDS AND/OR MODULATORS OF MICROBIAL INFECTIONS AND METHODS OF USING THE SAME | CD47, CGAS, FPR1 | MME 150/4885ACE 692/4885CPA1 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.