SCHEMBL20542997

SCHEMBL20542997

CCCCCCCCCCCCCCCCNC(=O)NC(CCCNC(=N)N)C(=O)NCCCCCCCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SIRT6 Q8N6T7 1/20 0.56
▸ SIRT1 Q96EB6 1/20 0.56
▸ EPHX1 P07099 8/20 0.51
▸ RRM1 P23921 1/20 0.47
▸ DPP7 Q9UHL4 2/20 0.47
▸ GNAI3 P08754 1/20 0.45
▸ GNAO1 P09471 1/20 0.45
▸ GNAI1 P63096 1/20 0.45
▸ NOD1 Q9Y239 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ CPT2 P23786 1/20 0.43
▸ CPT1A P50416 1/20 0.43
▸ CPT1B Q92523 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20543106 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20542683 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20543104 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20542644 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20543146 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20542738 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20542995 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20542642 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20542681 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7
SCHEMBL20542740 1.00 SIRT6 (0.56) SIRT6SIRT1EPHX1RRM1DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180311342-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-11-01 — — US claimed
EP-3395365-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-10-31 — — EP claimed
US-20180311342-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-11-01 — — US disclosed
EP-3395365-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-10-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180311342-A1 IMMUNOSTIMULATING AGENT MYD88, TLR9, IL2 SIRT6 1830/4885SIRT1 1226/4885EPHX1 2378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback