SCHEMBL20543155

SCHEMBL20543155

CCCCCCCCCCCCCCCCCCCCCC(=O)NC(CCCN)C(=O)NCCCCCCCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SIRT6 Q8N6T7 1/20 0.69
▸ SIRT1 Q96EB6 1/20 0.69
▸ TLR2 O60603 1/20 0.65
▸ GRIA1 P42261 1/20 0.60
▸ LPAR3 Q9UBY5 4/20 0.60
▸ NMT2 O60551 2/20 0.59
▸ NMT1 P30419 2/20 0.59
▸ LPAR1 Q92633 2/20 0.58
▸ SLC6A5 Q9Y345 1/20 0.56
▸ NOD1 Q9Y239 2/20 0.56
▸ GNAI3 P08754 1/20 0.56
▸ GNAO1 P09471 1/20 0.56
▸ GNAI1 P63096 1/20 0.56
▸ RRM1 P23921 1/20 0.55
▸ GLP1R P43220 3/20 0.54
▸ CHRND Q07001 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25457033 1.00 SIRT6 (0.69) SIRT6SIRT1TLR2GRIA1LPAR3
SCHEMBL17751871 1.00 SIRT6 (0.69) SIRT6SIRT1TLR2GRIA1LPAR3
SCHEMBL20543154 1.00 SIRT6 (0.69) SIRT6SIRT1TLR2GRIA1LPAR3
SCHEMBL17751797 1.00 SIRT6 (0.69) SIRT6SIRT1TLR2GRIA1LPAR3
SCHEMBL17749154 1.00 SIRT6 (0.69) SIRT6SIRT1TLR2GRIA1LPAR3
Hydrochloric Acid SCHEMBL20542880 0.99 SIRT6 (0.67) SIRT6SIRT1TLR2GRIA1LPAR3
Hydrochloric Acid SCHEMBL20542877 0.99 SIRT6 (0.67) SIRT6SIRT1TLR2GRIA1LPAR3
SCHEMBL20542968 0.96 SIRT6 (0.76) SIRT6SIRT1TLR2GRIA1LPAR3
SCHEMBL20542882 0.96 SIRT6 (0.76) SIRT6SIRT1TLR2GRIA1LPAR3
SCHEMBL23519401 0.96 SIRT6 (0.76) SIRT6SIRT1TLR2GRIA1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180311342-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-11-01 — — US claimed
EP-3395365-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-10-31 — — EP claimed
US-20180311342-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-11-01 — — US disclosed
EP-3395365-A1 IMMUNOSTIMULATING AGENT AJINOMOTO CO., INC. (JP) 2018-10-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180311342-A1 IMMUNOSTIMULATING AGENT MYD88, TLR9, IL2 SIRT6 1830/4885SIRT1 1226/4885TLR2 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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