SCHEMBL20544114

SCHEMBL20544114

CC1CCC(C(C)(C)SC(C)(C(=O)O)c2ccccc2)C(=O)C1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39
HIF1A Q16665 1/20 0.36
MT-CO2 P00403 2/20 0.33
ALOX5 P09917 2/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9669676 0.77 CYP2C19 (0.39) CYP2C19CYP2C9HIF1AMT-CO2ALOX5
SCHEMBL18339262 0.72 ALDH1A1 (0.33)
SCHEMBL23531279 0.69 CDC25B (0.38) CYP2C19CYP2C9HIF1ACYP1A2CYP2D6
SCHEMBL29451210 0.69 CDC25B (0.38) CYP2C19CYP2C9HIF1ACYP1A2CYP2D6
SCHEMBL28037813 0.66 CYP1A2 (0.43) CYP2C19CYP2C9HIF1ACYP1A2CYP2D6
SCHEMBL31278068 0.65 TLR4 (0.33)
SCHEMBL31277753 0.65 TLR4 (0.33)
SCHEMBL31278453 0.65 TLR4 (0.33)
SCHEMBL6902851 0.65 TLR4 (0.33)
SCHEMBL28732307 0.65 SOAT1 (0.44) MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2828240-B1 COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE PERFUMING MOLECULES FIRMENICH & CIE (CH) 2018-10-31 EP claimed