Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740948 | 0.98 | LMNA (0.55) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL7802146 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL29125045 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL29061964 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL22655191 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL28504158 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL8340752 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL1740609 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL29124961 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 | |
| SCHEMBL28455785 | 0.96 | LMNA (0.58) | LMNAMAPTDGKAMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394139-A1 | POLYURETHANE COMPOSITION WITH LOWER PLASTICISER MIGRATION | Sika Technology AG (CH) | 2018-10-31 | — | — | EP | disclosed |