SCHEMBL20544238

SCHEMBL20544238

CCC[SiH](OCC(O)CO)C(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.34
KDM4E B2RXH2 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5390586 0.66 USP2 (0.38) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL6240929 0.62 LMNA (0.40) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL20477535 0.59 USP2 (0.41) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL374763 0.58
Propanol SCHEMBL29170937 0.58 USP2 (0.48) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL14396790 0.58
Propane SCHEMBL5154976 0.57 USP2 (0.58) USP2KDM4EDUSP3MEN1KMT2A
SCHEMBL38656757 0.57
Glycerin SCHEMBL6240926 0.57 LMNA (0.53) USP2LMNA
Propane SCHEMBL27657560 0.57 USP2 (0.46) USP2KDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1601723-B1 DILUENTS FOR FORMING CLEAR, WETTABLE SILICONE HYDROGEL ARTICLES JOHNSON & JOHNSON VISION CARE (US) 2018-10-31 EP disclosed