Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 3/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13911223 | 0.86 | SIGMAR1 (0.48) | ALDH1A1POLBMAPTSIGMAR1EPHX2 | |
| SCHEMBL21799476 | 0.86 | HTR2A (0.47) | ALDH1A1POLBMAPTNAAASLC2A1 | |
| Methane SCHEMBL3957153 | 0.85 | SIGMAR1 (0.47) | ALDH1A1POLBMAPTSIGMAR1EPHX2 | |
| SCHEMBL21799802 | 0.84 | HTR2A (0.50) | ALDH1A1POLBMAPTNAAASLC2A1 | |
| SCHEMBL21799659 | 0.84 | HTR2A (0.50) | ALDH1A1POLBMAPTNAAASLC2A1 | |
| SCHEMBL21799652 | 0.84 | HTR2A (0.50) | ALDH1A1POLBMAPTNAAASLC2A1 | |
| SCHEMBL21799549 | 0.84 | HTR2A (0.50) | ALDH1A1POLBMAPTNAAASLC2A1 | |
| SCHEMBL21799711 | 0.84 | HTR2A (0.50) | ALDH1A1POLBMAPTNAAASLC2A1 | |
| SCHEMBL21799658 | 0.84 | HTR2A (0.50) | ALDH1A1POLBMAPTNAAASLC2A1 | |
| Hydrochloric Acid SCHEMBL11489607 | 0.84 | SLC2A1 (0.60) | ALDH1A1POLBMAPTNAAASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11383084-B2 | Treatment of dermatological conditions via neuromodulation | PALO ALTO INVESTORS (US) | 2022-07-12 | — | — | US | disclosed |
| US-20180311499-A1 | Treatment of Dermatological Conditions via Neuromodulation | PALO ALTO INVESTORS | 2018-11-01 | — | — | US | disclosed |
| CN-104220421-A | Sulfonamide derivatives of benzylamine for the treatment of central nervous system disorders | ADAMED SP ZOO | 2014-12-17 | — | — | CN | disclosed |