Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858272 | 0.88 | HPGD (0.59) | HPGDADORA2AADORA2BADORA3PAX8 | |
| SCHEMBL20547890 | 0.86 | ADORA2A (0.55) | HPGDADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL22577530 | 0.84 | HPGD (0.48) | HPGDADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL20547896 | 0.81 | TYMP (0.61) | ADORA1 | |
| SCHEMBL20547959 | 0.81 | HPGD (0.35) | HPGDADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL22577553 | 0.80 | HPGD (0.38) | HPGDADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL18512868 | 0.80 | ADORA2A (0.54) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL20580087 | 0.80 | ADORA2A (0.54) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL1042637 | 0.80 | ADORA2A (0.54) | MEN1KMT2AADORA2AADORA2BADORA3 | |
| SCHEMBL14917346 | 0.80 | ADORA2A (0.54) | MEN1KMT2AADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018198084-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES | LUPIN LIMITED (IN) | 2018-11-01 | — | — | WO | disclosed |