Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.66 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.66 |
| ▸ | TNF | P01375 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099869 | 1.00 | CYP11B1 (0.66) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL30099891 | 0.84 | TNF (0.55) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL20547804 | 0.84 | TNF (0.55) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL30826274 | 0.84 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL4142913 | 0.84 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL30099863 | 0.83 | KCNH2 (0.53) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL22126105 | 0.83 | KCNH2 (0.53) | CYP11B1CYP11B2TNFLMNAHTT | |
| Hydrochloric Acid SCHEMBL31253891 | 0.82 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFLMNAHTT | |
| Bromide SCHEMBL31253900 | 0.82 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFLMNAHTT | |
| SCHEMBL22533982 | 0.82 | FGFR1 (0.49) | CYP11B1CYP11B2TNFLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200196602-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | US | claimed |
| EP-3615523-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | Bayer Aktiengesellschaft (DE) | 2020-03-04 | — | — | EP | claimed |
| WO-2018197692-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-11-01 | — | — | WO | claimed |
| US-11457629-B2 | Heteroarylphenylaminoquinolines and analogues | BAYER AKTIENGESELLSCHAFT (DE) | 2022-10-04 | — | — | US | disclosed |
| US-20200196602-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | US | disclosed |
| EP-3615523-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | Bayer Aktiengesellschaft (DE) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018197692-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | BAYER AKTIENGESELLSCHAFT (DE) | 2018-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200196602-A1 | HETEROARYLPHENYLAMINOQUINOLINES AND ANALOGUES | PIK3C3, DDT, CYP4X1 | CYP11B1 507/4885CYP11B2 288/4885TNF 4489/4885 |
| US-11457629-B2 | Heteroarylphenylaminoquinolines and analogues | PIK3C3, CYP4X1, CYP1A2 | CYP11B1 191/4885CYP11B2 104/4885TNF 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.