Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22126105 | 1.00 | KCNH2 (0.53) | KCNH2CYP11B1CYP11B2LMNANPC1 | |
| SCHEMBL30099869 | 0.83 | CYP11B1 (0.66) | CYP11B1CYP11B2LMNAHTTTNF | |
| SCHEMBL20547652 | 0.83 | CYP11B1 (0.66) | CYP11B1CYP11B2LMNAHTTTNF | |
| SCHEMBL28321000 | 0.81 | KCNH2 (0.56) | KCNH2CYP11B1CYP11B2LMNANPC1 | |
| SCHEMBL18997853 | 0.81 | KCNH2 (0.56) | KCNH2CYP11B1CYP11B2LMNANPC1 | |
| SCHEMBL22533982 | 0.80 | FGFR1 (0.49) | CYP11B1CYP11B2LMNANPC1RAB9A | |
| SCHEMBL13508745 | 0.77 | KCNH2 (0.75) | KCNH2CYP11B1CYP11B2LMNANPC1 | |
| SCHEMBL15330708 | 0.74 | SMN1; SMN2 (0.40) | CYP11B1CYP11B2HTTTP53MAPT | |
| SCHEMBL12770764 | 0.72 | KCNH2 (0.72) | KCNH2CYP11B1CYP11B2LMNANPC1 | |
| SCHEMBL19915916 | 0.71 | LMNA (0.55) | KCNH2CYP11B1CYP11B2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110603253-B | Heteroaryl phenylamino quinolines and analogs | 拜耳公司 | 2023-01-20 | — | — | CN | disclosed |