SCHEMBL20547686

SCHEMBL20547686

CC(=O)OC(F)C(Br)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29031303 0.77 TSHR (0.43) TSHRTDP1
SCHEMBL1063328 0.77
SCHEMBL28354535 0.77
SCHEMBL4863907 0.72 TSHR (0.43) TSHRTDP1
SCHEMBL452396 0.71
SCHEMBL12019080 0.70 TSHR (0.42) TSHRTDP1
SCHEMBL27937250 0.69 TSHR (0.46) TSHRTDP1
SCHEMBL4382076 0.69 TSHR (0.46) TSHRTDP1
SCHEMBL29031302 0.68 TSHR (0.40) TSHRTDP1
SCHEMBL701398 0.68 TSHR (0.40) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3615520-B1 METHODS MEXICHEM FLUOR SA DE CV (MX) 2023-11-15 EP claimed
US-11377432-B2 Method for preparing a tetrafluoro-1,2-epoxypropane MEXICHEM FLUOR S.A.DE C.V. (MX) 2022-07-05 US claimed
US-20200148654-A1 METHOD FOR PREPARING A TETRAFLUORO-1,2-EPOXYPROPANE MEXICHEM FLUOR S.A.DE C.V. (MX) 2020-05-14 US claimed
EP-3615520-A1 METHODS Mexichem Fluor S.A. de C.V. (MX) 2020-03-04 EP claimed
CN-110546142-A Method of producing a composite material MEXICHEM FLUOR SA DE CV 2019-12-06 CN claimed
WO-2018197897-A1 METHODS MEXICHEM FLUOR S.A. DE C.V. (MX) 2018-11-01 WO claimed
EP-3615520-B1 METHODS MEXICHEM FLUOR SA DE CV (MX) 2023-11-15 EP disclosed
US-11718597-B2 Method for preparing a tetrafluoro-1,2-epoxypropane MEXICHEM FLUOR S.A.DE C.V. (MX) 2023-08-08 US disclosed
US-20220289701-A1 METHOD FOR PREPARING A TETRAFLUORO-1,2-EPOXYPROPANE MEXICHEM FLUOR S.A.DE C.V (MX) 2022-09-15 US disclosed
US-11377432-B2 Method for preparing a tetrafluoro-1,2-epoxypropane MEXICHEM FLUOR S.A.DE C.V. (MX) 2022-07-05 US disclosed
US-20200148654-A1 METHOD FOR PREPARING A TETRAFLUORO-1,2-EPOXYPROPANE MEXICHEM FLUOR S.A.DE C.V. (MX) 2020-05-14 US disclosed
EP-3615520-A1 METHODS Mexichem Fluor S.A. de C.V. (MX) 2020-03-04 EP disclosed
CN-110546142-A Method of producing a composite material MEXICHEM FLUOR SA DE CV 2019-12-06 CN disclosed
WO-2018197897-A1 METHODS MEXICHEM FLUOR S.A. DE C.V. (MX) 2018-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11377432-B2 Method for preparing a tetrafluoro-1,2-epoxypropane RER1, RTN3, ESRRA TSHR 59/4885TDP1 2868/4885
US-20220289701-A1 METHOD FOR PREPARING A TETRAFLUORO-1,2-EPOXYPROPANE RER1, ESRRA, OXSR1 TSHR 22/4885TDP1 3340/4885
US-11718597-B2 Method for preparing a tetrafluoro-1,2-epoxypropane RER1, ESRRA, OXSR1 TSHR 22/4885TDP1 3340/4885
US-20200148654-A1 METHOD FOR PREPARING A TETRAFLUORO-1,2-EPOXYPROPANE RER1, RTN3, ESRRA TSHR 59/4885TDP1 2868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.