SCHEMBL20547866

Cn1ccn2c(=O)c3ncn([C@@H]4O[C@@H]5CO[Si](C(C)(C)C)(C(C)(C)C)O[C@H]5[C@H]4O[Si](C)(C)C(C)(C)C)c3nc12

nearest known ligand 0.34

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	STING1	Q86WV6	4/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20547765	0.87	STING1 (0.35)	STING1
SCHEMBL20547882	0.85	STING1 (0.38)	STING1
SCHEMBL20547719	0.82	STING1 (0.34)	STING1
SCHEMBL20547506	0.81	STING1 (0.51)	STING1
SCHEMBL11986885	0.80	STING1 (0.33)	STING1
SCHEMBL20548261	0.79	STING1 (0.43)	STING1
SCHEMBL17363528	0.77	PDE4A (0.44)	STING1
SCHEMBL17363529	0.77	PDE4A (0.44)	STING1
SCHEMBL20547879	0.77	STING1 (0.35)	STING1
SCHEMBL20547861	0.77	STING1 (0.41)	STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2018198084-A1	CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES	LUPIN LIMITED (IN)	2018-11-01	—	—	WO	disclosed