Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547765 | 0.91 | STING1 (0.35) | STING1ALDH1A1PDE3BPDE3A | |
| SCHEMBL1582124 | 0.78 | HINT1 (0.39) | STING1 | |
| SCHEMBL20547866 | 0.77 | STING1 (0.34) | STING1 | |
| SCHEMBL20547882 | 0.75 | STING1 (0.38) | STING1ALDH1A1PDE3BPDE3AMEN1 | |
| SCHEMBL20548093 | 0.73 | PDE5A (0.31) | STING1 | |
| SCHEMBL20547587 | 0.73 | MEN1 (0.48) | MEN1KMT2A | |
| SCHEMBL1582239 | 0.73 | CDK5 (0.38) | ALDH1A1PDE3AMEN1KMT2A | |
| SCHEMBL20547506 | 0.72 | STING1 (0.51) | STING1PDE3BPDE3A | |
| SCHEMBL20547719 | 0.72 | STING1 (0.34) | STING1 | |
| SCHEMBL12936680 | 0.72 | STING1 (0.47) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018198084-A1 | CYCLIC DI-NUCLEOTIDE COMPOUNDS WITH TRICYCLIC NUCLEOBASES | LUPIN LIMITED (IN) | 2018-11-01 | — | — | WO | disclosed |