Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 3/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.57 |
| ▸ | MME | P08473 | 3/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 2/20 | 0.47 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.43 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.42 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094101 | 1.00 | SLC1A3 (0.57) | SLC1A3SLC1A2MMECPA1SLC7A5 | |
| SCHEMBL28225423 | 0.85 | SLC1A3 (0.57) | SLC1A3SLC1A2MMECPA1SLC7A5 | |
| SCHEMBL743997 | 0.84 | SLC1A3 (0.43) | SLC1A3SLC1A2MMECPA1SLC7A5 | |
| SCHEMBL1650677 | 0.84 | SLC1A3 (0.43) | SLC1A3SLC1A2MMECPA1SLC7A5 | |
| SCHEMBL5870523 | 0.81 | MME (0.56) | SLC1A3SLC1A2MMECPA1SLC7A5 | |
| SCHEMBL307076 | 0.81 | MME (0.56) | SLC1A3SLC1A2MMECPA1SLC7A5 | |
| SCHEMBL7262370 | 0.81 | MME (0.56) | SLC1A3SLC1A2MMECPA1SLC7A5 | |
| SCHEMBL2015332 | 0.80 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC7A5SLC1A1ADRA1A | |
| SCHEMBL17387490 | 0.80 | SLC1A3 (0.57) | SLC1A3SLC1A2SLC7A5SLC1A1ADRA1A | |
| SCHEMBL276879 | 0.80 | SLC1A3 (0.73) | SLC1A3SLC1A2MMECPA1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615019-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2020-03-04 | — | — | EP | disclosed |
| WO-2018200625-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-11-01 | — | — | WO | disclosed |